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Article

A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis.

Zebrafish - 1 Mar 2010

Paik Elizabeth J, de Jong Jill L O, Pugach Emily, Opara Praise, Zon Leonard I

Abstract excerpt

cdx4, a caudal-related homeodomain-containing transcription factor, functions as a regulator of hox genes, thereby playing a critical role in anterior-posterior (A-P) patterning during embryogenesis. In zebrafish, homozygous deletion of the cdx4 gene results in a mutant phenotype known as kugelig, with aberrant A-P patterning and severe anemia characterized by decreased gata1 expression in the posterior lateral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20415644
DOI: 10.1089/zeb.2009.0643
PMCID: PMC2897134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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