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Article

[New perspectives on molecular and genic therapies in Down syndrome].

Medecine sciences : M/S - 1 Apr 2010

Delabar Jean Maurice

Abstract excerpt

Trisomy 21 was first described as a syndrome in the middle of the nineteenth century and associated to a chromosomic anomaly one hundred years later: the most salient feature of this syndrome is a mental retardation of variable intensity. Molecular mapping and DNA sequencing have allowed identifying the gene content of chromosome 21. Molecular quantitative analyses indicated that trisomy is inducing an...

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Identifiers

PMID: 20412741
DOI: 10.1051/medsci/2010264371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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