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Article

Common RyR2 variants associate with ventricular arrhythmias and sudden cardiac death in chronic heart failure.

Clinical science (London, England : 1979) - 4 Jun 2010

Ran Yuqin, Chen Jingzhou, Li Ning, Zhang Weili, Feng Li, Wang Rongrong, Hui Rutai, Zhang Shu, Pu Jielin

Abstract excerpt

Ca2+ cycling plays a critical role in heart failure and lethal arrhythmias. As susceptibility to sudden cardiac death is considered to be a heritable trait in general population, we have therefore investigated whether potentially functional variants of genes encoding RyR2 (ryanodine receptor 2) and the L-type Ca2+ channel are related to the risk of ventricular arrhythmias and sudden cardiac death in CHF (chronic...

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Source

Identifiers

PMID: 20408814
DOI: 10.1042/CS20090656

Genes

RYR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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