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Article

Common genetic variants in selected Ca²⁺ signaling genes and the risk of appropriate ICD interventions in patients with heart failure.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing - 1 Dec 2013

Francia Pietro, Adduci Carmen, Ricotta Agnese, Stanzione Rosita, Sensini Isabella, Uccellini Arianna, Frattari Alessandra, Balla Cristina, Cotugno Maria, Cappato Riccardo, Rubattu Speranza, Volpe Massimo

Abstract excerpt

PURPOSE: Defective Ca²⁺ handling in failing cardiomyocites predisposes patients with heart failure (HF) to ventricular arrhythmia. We investigated whether gene variants of Ca²⁺ handling proteins are associated with the occurrence of ventricular tachycardia/fibrillation (VT/VF) in HF patients implanted with a primary prevention implantable cardioverter-defibrillator (ICD). METHODS: One hundred thirty-six patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24048583
DOI: 10.1007/s10840-013-9827-1

Genes

CASQ2
PLN
RYR2

Provenance

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