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Article

Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease.

Heart rhythm - 1 Apr 2014

Refaat Marwan M, Aouizerat Bradley E, Pullinger Clive R, Malloy Mary, Kane John, Tseng Zian H

Abstract excerpt

BACKGROUND: Abnormal calcium handling plays a crucial role in arrhythmias, sudden cardiac arrest (SCA), and congestive heart failure (CHF). Calsequestrin 2 (CASQ2) mutations affect calcium release and initiate malignant ventricular arrhythmias (VAs) and SCA syndromes. Common single nucleotide polymorphisms (SNPs) in CASQ2 may be associated with SCA in patients with coronary artery disease (CAD). OBJECTIVE: The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24444446
DOI: 10.1016/j.hrthm.2014.01.015
PMCID: PMC3989347

Genes

CASQ2
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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