Article
Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases.
International journal of molecular sciences - 18 Apr 2022
Szentandrássy Norbert, Magyar Zsuzsanna É, Hevesi Judit, Bányász Tamás, Nánási Péter P, Almássy János
Abstract excerpt
Cardiac diseases are the leading causes of death, with a growing number of cases worldwide, posing a challenge for both healthcare and research. Therefore, the most relevant aim of cardiac research is to unravel the molecular pathomechanisms and identify new therapeutic targets. Cardiac ryanodine receptor (RyR2), the Ca2+ release channel of the sarcoplasmic reticulum, is believed to be a good therapeutic target...
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