Article
Paraoxonase 1 (PON1) polymorphisms and risk for migraine.
Journal of neurology - 1 Sept 2010
García-Martín Elena, Martínez Carmen, Serrador Mercedes, Alonso-Navarro Hortensia, Navacerrada Francisco, Agúndez José A G, Jiménez-Jiménez Félix Javier
Abstract excerpt
The polymorphic enzyme human serum paraoxonase 1 (PON1), encoded by the gene PON1 (chromosome 7q21.3) plays a role as an antioxidant molecule through several mechanisms. Because oxidative stress has been implicated in the pathogenesis of migraine, we have investigated the possible association bet...
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