Article
Association Study of ANRIL Genetic Variants and Multiple Sclerosis.
Journal of molecular neuroscience : MN - 1 May 2018
Rezazadeh Maryam, Gharesouran Jalal, Moradi Mohsen, Noroozi Rezvan, Omrani Mir Davood, Taheri Mohammad, Ghafouri-Fard Soudeh
Abstract excerpt
Multiple sclerosis (MS) is an autoimmune disorder of central nervous system with several genetic and environmental risk factors. Genes with regulatory roles on immune system have been implicated in its pathogenesis. Recently, long non-coding RNAs (lncRNAs) have been demonstrated to control some aspects of immune response. Among them is antisense non-coding RNA in the INK4 locus (ANRIL) whose involvement in NF-κB...
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