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Article

NRAMP1 (SLC11A1) gene polymorphisms that correlate with autoimmune versus infectious disease susceptibility in tuberculosis and rheumatoid arthritis.

International journal of immunogenetics - 1 Feb 2009

Ates O, Dalyan L, Müsellim B, Hatemi G, Türker H, Ongen G, Hamuryudan V, Topal-Sarikaya A

Abstract excerpt

NRAMP1 gene has multiple pleiotropic effects on macrophage activation pathways. These pleiotropic effects may increase resistance to infections such as tuberculosis (TB), but may also lead to susceptibility of autoimmune diseases such as rheumatoid arthritis (RA). It has been hypothesized that allele 3 would be associated with autoimmune diseases, whereas allele 2 would be associated with infectious diseases, and...

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Source

Identifiers

PMID: 19055603
DOI: 10.1111/j.1744-313X.2008.00814.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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