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Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma

27 Jan 2010

Abstract excerpt

Caspase 8 and survivin are known as key molecules of apoptosis in hepatocellular carcinoma (HCC). The purpose of the present study was to investigate the relationship between promoter methylation and expression and apoptotic function of caspase 8 and survivin in HCC. Promoter methylation of the caspase 8 and survivin gene was analyzed in 73 primary HCC using methylation-specific polymerase chain reaction. The...

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PMID: 20403046
DOI: 10.1111/j.1440-1827.2009.02507.x

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