Article
Nuclear survivin promoted by acetylation is associated with the aggressive phenotype of oral squamous cell carcinoma.
Cell cycle (Georgetown, Tex.) - 3 May 2017
Liu Shuli, Shi Lei, Yang Xi, Ye Dongxia, Wang Tong, Dong Cunshan, Guo Wenzheng, Liao Yueling, Song Hongyong, Xu Dongliang, Hu Jingzhou, Zhang Zhiyuan, Deng Jiong
Abstract excerpt
Defects in apoptotic pathway contribute to development and progression of oral cancer. Survivin, a member of the inhibitors of apoptosis protein (IAP) family, is increased in many types of cancers. However, it is unclear whether increased survivin is associated with oral squamous cell carcinomas (OSCC), and what mechanisms may involve in. In this study, we examined survivin expression in OSCC compared with normal...
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