Article
Survivin expression in esophageal cancer: correlation with p53 mutations and promoter polymorphism.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2009
Yang Xiaoya, Xiong Gang, Chen Xuedan, Xu Xueqing, Wang Kai, Fu Yong, Yang Kang, Bai Yun
Abstract excerpt
Survivin is an inhibitor of apoptosis protein, which is selectively up-regulated in various cancers including esophageal cancer. The underlying mechanism of survivin overexpression in cancers is still unclear. We investigated resected tumor specimens from 100 esophageal cancer patients. Reverse transcription polymerase chain reaction was performed to evaluate survivin gene expression. Polymerase chain...
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