Article
Application of continuous culture for measuring the effect of environmental stress on mutation frequency in Mycobacterium tuberculosis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Bacon Joanna, Hatch Kim A, Allnutt Jon
Abstract excerpt
The ability of all pathogens to survive within the host is key to their success in establishing disease. Environmental conditions that affect the growth of a pathogen in the host include nutrient status, environmental pH, oxygen availability, and host defences. Studying the response of Mycobacterium tuberculosis (M. tuberculosis) exposed to these relevant host conditions in vitro will further increase our...
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