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Article

Hypoxia activates a latent circuit for processing gustatory information in C. elegans.

Nature neuroscience - 1 May 2010

Pocock Roger, Hobert Oliver

Abstract excerpt

Dedicated neuronal circuits enable animals to engage in specific behavioral responses to environmental stimuli. We found that hypoxic stress enhanced gustatory sensory perception via previously unknown circuitry in Caenorhabditis elegans. The hypoxia-inducible transcription factor HIF-1 upregulated serotonin (5-HT) expression in specific sensory neurons that are not normally required for chemosensation. 5-HT...

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Identifiers

PMID: 20400959
DOI: 10.1038/nn.2537
PMCID: PMC3733994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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