Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.

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Article

Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.

Blood - 1 Jun 1991

Cesano A, O'Connor R, Lange B, Finan J, Rovera G, Santoli D

Abstract excerpt

The aim of this study was to analyze the homing and progression patterns of childhood acute lymphoblastic leukemias (ALL) in mice with severe combined immunodeficiency (SCID). Upon intraperitoneal (IP) transfer, cells from relapse samples of three children with T-lineage ALL spread hematogenously...

Topics

Animals
Antigens, Surface
Cell Line
Child
Female
Gene Rearrangement, B-Lymphocyte
Genotype
Humans
Immunologic Deficiency Syndromes
Islets of Langerhans
Kidney
Liver
Male
Mice
Mice, Mutant Strains
Neoplasm Transplantation
Phenotype
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Open in PubMed

Identifiers

PMID: 2039829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2039829-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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