Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.

Blood - 1 Jun 1991

Cesano A, O'Connor R, Lange B, Finan J, Rovera G, Santoli D

Abstract excerpt

The aim of this study was to analyze the homing and progression patterns of childhood acute lymphoblastic leukemias (ALL) in mice with severe combined immunodeficiency (SCID). Upon intraperitoneal (IP) transfer, cells from relapse samples of three children with T-lineage ALL spread hematogenously and infiltrated the non-lymphoid and/or lymphoid organs with a pattern reminiscent of the human clinical disease....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Child
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kidney

Share to Mice, Mutant Strains

Share to Phenotype

Source

Identifiers

PMID: 2039829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.PMID 2039829Read ↗

Modeling the Initiation and Progression of Human Acute Leukemia in MiceSemantic proximity Read ↗

Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biologySemantic proximity Read ↗

Growth and biologic properties of karyotypically defined subcategories of adult acute lymphocytic leukemia in mice with severe combined immunodeficiency.Semantic proximity Read ↗

Differential kinetics of engraftment and induction of CD10 on human pre-B leukemia cell lines in immune deficient scid mice.Semantic proximity Read ↗

Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcomeSemantic proximity Read ↗

Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.Semantic proximity Read ↗

Childhood all blasts retain phenotypic and genotypic characteristics upon long-term serial passage in NOD/SCID mice.Semantic proximity Read ↗

Lineage switch in a childhood T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness.Semantic proximity Read ↗

Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagationSemantic proximity Read ↗

Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.