Article
Childhood all blasts retain phenotypic and genotypic characteristics upon long-term serial passage in NOD/SCID mice.
Pediatric hematology and oncology - 1 Dec 2000
Borgmann A, Baldy C, von Stackelberg A, Beyermann B, Fichtner I, Nürnberg P, Henze G
Abstract excerpt
For children with an early bone marrow relapse or relapsed T-cell acute lymphoblastic leukemia (ALL), allogeneic bone marrow transplantation (BMT) is currently the only therapeutic option with a curative approach. Here, the graft versus leukemia (GvL) effect seems to play an important role for long-term immunological control of leukemia. If a bone marrow donor is not available, autologous stem cell...
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