Article
Patient HLA-DRB1* and -DQB1* allele and haplotype association with hepatitis C virus persistence and clearance.
The Journal of general virology - 1 Aug 2010
Ali Lubna, Mansoor Atika, Ahmad Nafees, Siddiqi Saima, Mazhar Kehkashan, Muazzam Ambreen G, Qamar Raheel, Khan Khalid M
Abstract excerpt
Hepatitis C virus (HCV) infection is prevalent throughout the world and interferon (IFN)-based treatments are currently the only therapeutic option. However, depending upon variations in their human leukocyte antigen (HLA), some patients do not respond well to IFN therapy. The current study evaluated the HLA allele and haplotype distribution of 204 HCV-seropositive individuals from Islamabad, Pakistan, who were...
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