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Article

Association between HLA class II genotype and spontaneous clearance of hepatitis C viraemia.

Journal of hepatology - 1 Aug 1998

Cramp M E, Carucci P, Underhill J, Naoumov N V, Williams R, Donaldson P T

Abstract excerpt

BACKGROUND/AIMS: Hepatitis C virus (HCV) infection becomes chronic in most cases, with only 10-20% of those infected not developing persistent viraemia. The immune response to HCV may be an important determinant of disease resolution and can be influenced by a number of host factors. The aim of this study was to assess the role of host HLA class II type in influencing viral clearance or susceptibility to chronic...

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PMID: 9722201
DOI: 10.1016/s0168-8278(98)80005-6

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