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Article

Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids.

The Journal of biological chemistry - 11 Jun 2010

Veiga-da-Cunha Maria, Tyteca Donatienne, Stroobant Vincent, Courtoy Pierre J, Opperdoes Fred R, Van Schaftingen Emile

Abstract excerpt

Our goal was to identify the reaction catalyzed by NAT8 (N-acetyltransferase 8), a putative N-acetyltransferase homologous to the enzyme (NAT8L) that produces N-acetylaspartate in brain. The almost exclusive expression of NAT8 in kidney and liver and its predicted association with the endoplasmic reticulum suggested that it was cysteinyl-S-conjugate N-acetyltransferase, the microsomal enzyme that catalyzes the...

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Source

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Identifiers

PMID: 20392701
DOI: 10.1074/jbc.M110.110924
PMCID: PMC2881811

Genes

NAT8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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