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Article

Combined functional genome survey of therapeutic targets for hepatocellular carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2010

Satow Reiko, Shitashige Miki, Kanai Yae, Takeshita Fumitaka, Ojima Hidenori, Jigami Takafumi, Honda Kazufumi, Kosuge Tomoo, Ochiya Takahiro, Hirohashi Setsuo, Yamada Tesshi

Abstract excerpt

PURPOSE: The outcome of patients with advanced hepatocellular carcinoma (HCC) has remained unsatisfactory. Patients with HCC suffer from chronic hepatitis or liver cirrhosis, and their reserve liver function is often limited. EXPERIMENTAL DESIGN: To develop new therapeutic agents that act specifically on HCC but interfere only minimally with residual liver function, we searched for genes that were upregulated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20388846
DOI: 10.1158/1078-0432.CCR-09-2214

Genes

TPX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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