Article

Identification of transcriptional landscapes and functions of the inhibition of ARHGEF2 in hepatocellular carcinoma cells

2022-08-18

Abstract excerpt

The RHO guanine exchange factor ARHGEF2 has exchange activity toward RHOA, which is essential for the development of cancers such as liver cancer. However, the potential functions and mechanisms of ARHGEF2 in the progression of liver cancer are largely unknown. In this study, we identified the transcriptional landscapes of hepatocellular carcinoma cells treated with ARHGEF2 shRNAs. The gene enrichment assays such...

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Literature Corpus work: ba11a9ed-9d1e-59bd-ba95-3f7fdcbac475
DOI: 10.1101/2022.08.18.504433

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