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Hepatocellular Carcinoma: Molecular Pathways and New Therapeutic Targets

1 May 2005

Abstract excerpt

Hepatocellular carcinoma is often diagnosed at an advanced stage, when it is not amenable to curative therapies. There is no effective chemotherapy. Advances in cancer biology suggest that a limited number of pathways are responsible for initiating and maintaining dysregulated cell proliferation, which is the major cellular alteration responsible for the cancer phenotype. New treatments in development target...

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PMID: 15918149
DOI: 10.1055/s-2005-871200

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