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Polyploidy: The Link Between Senescence and Cancer

1 Feb 2010

Abstract excerpt

Polyploidy, a state of increased number of chromosomes, occurs often in plants and less frequently in animals. Polyploidization is recognized as a part of a developmental program and can be achieved via different mechanisms bypassing certain stages of the cell cycle. However, polyploidization also accompanies some pathological conditions as well as ageing. It is believed that tetraploid cells precede aneuploid...

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Share to Chromosomal and Genetic Variations
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PMID: 20388083
DOI: 10.2174/138161210790883714

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