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Article

Characterization of the cell-penetrating properties of the Epstein-Barr virus ZEBRA trans-activator.

The Journal of biological chemistry - 25 Jun 2010

Rothe Romy, Liguori Lavinia, Villegas-Mendez Ana, Marques Bruno, Grunwald Didier, Drouet Emmanuel, Lenormand Jean-Luc

Abstract excerpt

The Epstein-Barr virus basic leucine zipper transcriptional activator ZEBRA was shown recently to cross the outer membrane of live cells and to accumulate in the nucleus of lymphocytes. We investigated the potential application of the Epstein-Barr virus trans-activator ZEBRA as a transporter protein to facilitate transduction of cargo proteins. Analysis of different truncated forms of ZEBRA revealed that the...

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Identifiers

PMID: 20385549
DOI: 10.1074/jbc.M110.101550
PMCID: PMC2888435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of the cell-penetrating properties of the Epstein-Barr virus ZEBRA trans-activator.PMID 20385549Read ↗

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The Epstein-Barr virus ZEBRA protein activates transcription from the early lytic F promoter by binding to a promoter-proximal AP-1-like site.Semantic proximity Read ↗

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