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Article

A toolkit for rapid gene mapping in the nematode Caenorhabditis briggsae.

BMC genomics - 13 Apr 2010

Koboldt Daniel C, Staisch Julia, Thillainathan Bavithra, Haines Karen, Baird Scott E, Chamberlin Helen M, Haag Eric S, Miller Raymond D, Gupta Bhagwati P

Abstract excerpt

BACKGROUND: The nematode C. briggsae serves as a useful model organism for comparative analysis of developmental and behavioral processes. The amenability of C. briggsae to genetic manipulations and the availability of its genome sequence have prompted researchers to study evolutionary changes in gene function and signaling pathways. These studies rely on the availability of forward genetic tools such as mutants...

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PMID: 20385026
DOI: 10.1186/1471-2164-11-236
PMCID: PMC2864247

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