Article
The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.
Molecular and cellular biology - 1 Jun 1991
Williams F E, Varanasi U, Trumbly R J
Abstract excerpt
Mutations of yeast CYC8 or TUP1 genes greatly reduce the degree of glucose repression of many genes and affect other regulatory pathways, including mating type. The predicted CYC8 protein contains 10 copies of the 34-amino-acid tetratricopeptide repeat unit, and the predicted TUP1 protein has six repeated regions found in the beta subunit of heterotrimeric G proteins. The absence of DNA-binding motifs and the...
Topics
- Blotting, Western
- Cloning, Molecular
- DNA-Binding Proteins
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Fungal Proteins
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genotype
- Glucose
- Macromolecular Substances