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Article

Acquisition of the ability to assimilate mannitol by Saccharomyces cerevisiae through dysfunction of the general corepressor Tup1-Cyc8.

Applied and environmental microbiology - 1 Jan 2015

Chujo Moeko, Yoshida Shiori, Ota Anri, Murata Kousaku, Kawai Shigeyuki

Abstract excerpt

Saccharomyces cerevisiae normally cannot assimilate mannitol, a promising brown macroalgal carbon source for bioethanol production. The molecular basis of this inability remains unknown. We found that cells capable of assimilating mannitol arose spontaneously from wild-type S. cerevisiae during prolonged culture in mannitol-containing medium. Based on microarray data, complementation analysis, and cell growth...

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Identifiers

PMID: 25304510
DOI: 10.1128/AEM.02906-14
PMCID: PMC4272704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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