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Article

Tcc1p, a novel protein containing the tetratricopeptide repeat motif, interacts with Tup1p to regulate morphological transition and virulence in Candida albicans.

Eukaryotic cell - 1 Nov 2006

Kaneko Aki, Umeyama Takashi, Utena-Abe Yuki, Yamagoe Satoshi, Niimi Masakazu, Uehara Yoshimasa

Abstract excerpt

The transcriptional factor CaTup1p represses many genes involved in intracellular processes, including the yeast-hypha transition, in the human fungal pathogen Candida albicans. Using tandem affinity purification technology, we identified a novel protein that interacts with CaTup1p, named Tcc1p (Tup1p complex component). Tcc1p is a C. albicans-specific protein with a 736-amino-acid polypeptide with four...

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Identifiers

PMID: 16998076
DOI: 10.1128/EC.00151-06
PMCID: PMC1694794

Genes

TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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