Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The exon 3 deleted growth hormone receptor gene is associated with small birth size and early pubertal onset in healthy boys.

The Journal of clinical endocrinology and metabolism - 1 Jun 2010

Sørensen Kaspar, Aksglaede Lise, Petersen Jørgen Holm, Leffers Henrik, Juul Anders

Abstract excerpt

CONTEXT: The GH/IGF-I axis influences gonadal development and function. Recently, a deletion of exon 3 in the GH receptor gene (GHRd3) has been linked to increased responsiveness to GH. OBJECTIVE: Our objective was to evaluate the influence of the GHRd3 gene on birth size and pubertal onset. DESIGN AND SETTING: We conducted a cross-sectional study, part of The COPENHAGEN Puberty Study, at a tertiary center for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth Weight
Share to Follicle Stimulating Hormone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Insulin-Like Growth Factor I

Share to Luteinizing Hormone

Share to Puberty

Share to Receptors, Somatotropin

Share to Testosterone

Source

Identifiers

PMID: 20382688
DOI: 10.1210/jc.2009-2484

Genes

GHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The exon 3 deleted growth hormone receptor gene is associated with small birth size and early pubertal onset in healthy boys.PMID 20382688Read ↗

Association between GH receptor polymorphism (exon 3 deletion), serum IGF1, semen quality, and reproductive hormone levels in 838 healthy young men.Semantic proximity Read ↗

Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty.Semantic proximity Read ↗

The growth hormone receptor exon 3 polymorphism is not associated with height or metabolic traits in healthy young adults.Semantic proximity Read ↗

The growth hormone receptor gene deleted for exon three (GHRd3) polymorphism is associated with birth and placental weight.Semantic proximity Read ↗

The Presence of the d3-Growth Hormone Receptor Polymorphism Is Negatively Associated with Fetal Growth but Positively Associated with Postnatal Growth in Healthy SubjectsSemantic proximity Read ↗

The growth hormone receptor exon 3-deleted/full-length polymorphism and response to growth hormone therapy in prepubertal idiopathic short children.Semantic proximity Read ↗

GH receptor d3 polymorphism in Dutch patients with MPHD and IGHD born small or appropriate for gestational age.Semantic proximity Read ↗

The Exon 3-Deleted Growth Hormone Receptor (d3GHR) Polymorphism - a Favorable Backdoor Mechanism for the GHR FunctionSemantic proximity Read ↗

Association of the growth hormone receptor d3-variant and catch-up growth of preterm infants with birth weight of less than 1500 grams.Semantic proximity Read ↗

Analysis of the d3-growth hormone receptor polymorphism in large cohorts of small, appropriate and large for gestational age newborns.Semantic proximity Read ↗

Growth hormone receptor exon 3 isoforms and their implication in growth disorders and treatment.Semantic proximity Read ↗

The distribution of exon 3-deleted/full-length growth hormone receptor polymorphism in the Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.