Article
Association of the growth hormone receptor d3-variant and catch-up growth of preterm infants with birth weight of less than 1500 grams.
The Journal of clinical endocrinology and metabolism - 1 Nov 2007
Schreiner Felix, Stutte Sonja, Bartmann Peter, Gohlke Bettina, Woelfle Joachim
Abstract excerpt
BACKGROUND: Preterm infants with very low birth weight frequently exhibit impaired longitudinal growth during the first years of life. Recently, the d3-isoform (genomic deletion of exon 3) of the GH receptor (GHR) has been linked to an increased responsiveness to GH. OBJECTIVE: Our objective was to test whether the GHRd3 isoform is associated with postnatal catch-up growth in very low birth weight preterm...
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