The Presence of the d3-Growth Hormone Receptor Polymorphism Is Negatively Associated with Fetal Growth but Positively Associated with Postnatal Growth in Healthy Subjects

Abstract excerpt

CONTEXT: A common polymorphism in the GH receptor (GHR) gene has been linked to increased growth response in GH-treated patients. No former study has focused on the association to prenatal growth. OBJECTIVE: The aim of the study was to evaluate the association between the d3-GHR isoforms and spontaneous pre- and postnatal growth. DESIGN: A prospective study was conducted on third-trimester fetal growth velocity...

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