Article
Sex differences in striatal dopaminergic function within heterozygous mutant dopamine transporter knock-out mice.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jun 2008
Ji Jing, Dluzen Dean E
Abstract excerpt
The issue of whether a deletion of the dopamine transporter (DAT) allele (+/- DAT) would differentially alter striatal dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) concentrations and DA release upon potassium and methamphetamine (MA) stimulation between male and female mice was examined. Striatal DA and DOPAC concentrations of female +/- DAT mice were significantly decreased as compared with wild type...
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