Article
Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness study).
Journal of the American College of Cardiology - 22 Jun 2010
Epstein Robert S, Moyer Thomas P, Aubert Ronald E, O Kane Dennis J, Xia Fang, Verbrugge Robert R, Gage Brian F, Teagarden J Russell
Abstract excerpt
OBJECTIVES: This study was designed to determine whether genotype testing for patients initiating warfarin treatment will reduce the incidence of hospitalizations, including those due to bleeding or thromboembolism. BACKGROUND: Genotypic variations in CYP2C9 and VKORC1 have been shown to predict warfarin dosing, but no large-scale studies have prospectively evaluated the clinical effectiveness of genotyping in...
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