Article
Comparing the clinical utility of pharmacogenomic genotyping and next generation sequencing in a military health system adult medicine clinic.
Pharmacogenomics - 1 Jan 2024
Saunders David, Hellwig Lydia D, Pagani Austin, De Castro Mauricio, Haigney Mark, Poon Lucas, Ehat Nate, Heroy Andrew, Libbus Joya, Fox Keiko, Kalra Sachi, Arnold Thomas B, Turner Clesson, Black John Logan, Scherer Steven E, Moyer Ann M
Abstract excerpt
INTRODUCTION: Pharmacogenetic (PGx) screening is intended to optimize drug efficacy and reduce adverse drug reactions. Current screening options include genotyping assays for preselected PGx variants and broader next-generation sequencing panels (NGS). Few studies have directly compared preemptive PGx screening methods. MATERIALS AND METHODS: The two PGx methods were compared in a cross-sectional study of adult...
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