Article
Haplotype inference in complex pedigrees.
Journal of computational biology : a journal of computational molecular cell biology - 1 Mar 2010
Kirkpatrick Bonnie, Halperin Eran, Karp Richard M
Abstract excerpt
Despite the desirable information contained in complex pedigree data sets, analysis methods struggle to efficiently process these data. The attractiveness of pedigree data is their power for detecting rare variants, particularly in comparison with studies of unrelated individuals. In addition, rather than assuming individuals in a study are unrelated, knowledge of their relationships can avoid spurious results...
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