Article
Drug resistance mutations of HIV type 1 non-B viruses to integrase inhibitors in treatment-naive patients from sub-saharan countries and discordant interpretations.
AIDS research and human retroviruses - 1 Sept 2012
Monleau Marjorie, Aghokeng Avelin F, Nkano Benedicte A, Chaix Marie-Laure, Peeters Martine
Abstract excerpt
The routine use of integrase inhibitors in sub-Saharan Africa where HIV-1 non-B viruses predominate is limited, but evaluating their effectiveness on HIV-1 subtypes and CRFs that circulate in this region is essential. We here analyzed 97 integrase sequences from HIV-1 non-B-infected individuals from African countries. Using currently available interpretation algorithms (ANRS, HIVdb, and Rega), we identified the...
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