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Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model

21 Dec 2017

Abstract excerpt

Rift Valley fever phlebovirus (RVFV) causes high rates of abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or blindness in humans. Viral transmission occurs via mosquito vectors in endemic areas, which necessitates regular vaccination of susceptible livestock animals to prevent the RVF outbreaks. Although ZH501 strain has been used as a challenge strain for past vaccine...

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PMID: 29267298
DOI: 10.1371/journal.pone.0189250

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