Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Follicle stimulating hormone receptor mutations and reproductive disorders.

Progress in molecular biology and translational science - 1 Jan 2009

Tao Ya-Xiong, Segaloff Deborah L

Abstract excerpt

The follicle stimulating hormone receptor (FSHR) plays a critical role in reproductive function. In the males, FSH supports spermatogenesis, whereas in females, FSH is absolutely required for ovarian follicle growth. In females, inactivating mutations in the FSHR result in ovarian dysgenesis with amenorrhea and infertility. The few males reported with severe inactivating mutations exhibited varying spermatogenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to FSHR gene
Share to Mutant Proteins
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, FSH

Share to Reproduction

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 20374735
DOI: 10.1016/S1877-1173(09)89005-4

Genes

FSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Follicle stimulating hormone receptor mutations and reproductive disorders.PMID 20374735Read ↗

Follicle-stimulating hormone ligand and receptor mutations, and gonadal dysfunction.Semantic proximity Read ↗

Inactivating FSH receptor mutations and gonadal dysfunction.Semantic proximity Read ↗

The molecular basis of impaired follicle-stimulating hormone action: evidence from human mutations and mouse models.Semantic proximity Read ↗

Mutations of follicle stimulating hormone-beta and its receptor in human and mouse: genotype/phenotype.Semantic proximity Read ↗

[Mutations in the follicle-stimulating hormone receptor genes in patients with gonadal dysfunction].Semantic proximity Read ↗

Mutations and polymorphisms in FSH receptor: functional implications in human reproduction.Semantic proximity Read ↗

Functional and clinical consequences of mutations in the FSH receptor.Semantic proximity Read ↗

Mutations and polymorphisms of the FSH receptor (FSHR) gene: clinical implications in female fecundity and molecular biology of FSHR protein and gene.Semantic proximity Read ↗

The impact of follicle-stimulating hormone receptor mutations on female ovarian function and pregnancy outcomes: a systematic review†.Semantic proximity Read ↗

Mutations of LH and FSH receptors.Semantic proximity Read ↗

Molecular genetic, biochemical, and clinical implications of gonadotropin receptor mutations.Semantic proximity Read ↗

Impact of follicle stimulating hormone receptor variants in fertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.