Article
Functional and clinical consequences of mutations in the FSH receptor.
Molecular and cellular endocrinology - 20 Dec 1996
Gromoll J, Simoni M, Nordhoff V, Behre H M, De Geyter C, Nieschlag E
Abstract excerpt
The follicle-stimulating hormone (FSH) is essential for normal gametogenesis. In females FSH is required for ovarian development and follicle maturation whereas in males FSH determines Sertoli cell number and quantitatively and qualitatively normal spermatogenesis. FSH action is mediated by a G-protein coupled receptor expressed solely in granulosa and Sertoli cells. The FSH-receptor (FSHR) gene is localized on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
