Article
Mutations of follicle stimulating hormone-beta and its receptor in human and mouse: genotype/phenotype.
Molecular and cellular endocrinology - 30 Mar 2000
Layman L C, McDonough P G
Abstract excerpt
The pituitary gonadotropin follicle stimulating hormone (FSH) interacts with its membrane-bound receptor, to produce biologic effects. Traditional functions of FSH include, follicular development and estradiol production in females and the regulation of Sertoli cell action and spermatogenesis in males. FSHbeta knock-out mice and transgenic mice, serve as models for FSH deficiency and excess, respectively. In...
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