Article
Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics.
Microcirculation (New York, N.Y. : 1994) - 1 Apr 2010
Dahl Kris Noel, Kalinowski Agnieszka, Pekkan Kerem
Abstract excerpt
Endothelial cells are stimulated by shear stress throughout the vasculature and respond with changes in gene expression and by morphological reorganization. Mechanical sensors of the cell are varied and include cell surface sensors that activate intracellular chemical signaling pathways. Here, possible mechanical sensors of the cell including reorganization of the cytoskeleton and the nucleus are discussed in...
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