Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA oxidative damage of neoplastic rat liver lesions.

Oncology reports - 1 May 2010

Marengo Barbara, De Ciusis Chiara, Ricciarelli Roberta, Romano Paola, Passalacqua Mario, Marinari Umberto M, Pronzato Maria A, Domenicotti Cinzia

Abstract excerpt

Hepatic lesions, experimentally-induced in Fisher 344 (F344) and Brown Norway (BN) rats, respectively, susceptible and resistant to liver carcinogenesis, progress differently to hepatocellular carcinoma (HCC). The mechanisms responsible for the acquisition of the resistant phenotype are not completely clear. Herein, we show that in F344 rats subjected to carcinogenic treatment, angiogenesis and DNA oxidation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 8-Hydroxy-2'-Deoxyguanosine
Share to Deoxyguanosine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glutathione

Share to Liver Neoplasms, Experimental

Share to Precancerous Conditions

Share to Rats, Inbred BN

Share to Rats, Inbred F344

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 20372836
DOI: 10.3892/or_00000756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA oxidative damage of neoplastic rat liver lesions.PMID 20372836Read ↗

Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.Semantic proximity Read ↗

The BN rat strain carries dominant hepatocarcinogen resistance loci.Semantic proximity Read ↗

Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.Semantic proximity Read ↗

Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal.Semantic proximity Read ↗

Biomarkers of aging: correlation of DNA I-compound levels with median lifespan of calorically restricted and ad libitum fed rats and mice.Semantic proximity Read ↗

Significance of Hepatic Preneoplasia in Risk Identification and Early Detection of Neoplasia *Semantic proximity Read ↗

Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes.Semantic proximity Read ↗

Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis.Semantic proximity Read ↗

Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma.Semantic proximity Read ↗

Phenotypic reversion of rat neoplastic liver nodules is under genetic control.Semantic proximity Read ↗

Histogenesis and the role of p53 and K-ras mutations in hepatocarcinogenesis by glyceryl trinitrate (nitroglycerin) in male F344 rats.Semantic proximity Read ↗

Enhancement of DEN-induced liver tumorigenesis in heme oxygenase-1 G143H mutant transgenic mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.