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Article

Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.

Carcinogenesis - 1 Aug 2008

Calvisi Diego F, Pinna Federico, Ladu Sara, Pellegrino Rossella, Muroni Maria R, Simile Maria M, Frau Maddalena, Tomasi Maria L, De Miglio Maria R, Seddaiu Maria A, Daino Lucia, Sanna Valeria, Feo Francesco, Pascale Rosa M

Abstract excerpt

Mounting evidence underlines the role of inducible nitric oxide synthase (iNOS) in hepatocellular carcinoma (HCC) development, but its functional interactions with pathways involved in HCC progression remain uninvestigated. Here, we analyzed in preneoplastic and neoplastic livers from Fisher 344 and Brown Norway rats, possessing different genetic predisposition to HCC, in transforming growth factor-alpha...

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PMID: 18579559
DOI: 10.1093/carcin/bgn155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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