Article
Association of the orphan nuclear receptor NR4A1 with tardive dyskinesia.
Psychiatric genetics - 1 Feb 2010
Novak Gabriela, Gallo Alexandra, Zai Clement C, Meltzer Herbert Y, Lieberman Jeffrey A, Potkin Steven G, Voineskos Aristotle N, Remington Gary, Kennedy James L, Levesque Daniel, Le Foll Bernard
Abstract excerpt
Recent evidence has identified the NR4A1 (NUR77, NGFI-B) gene as a strong candidate for involvement in tardive dyskinesia (TD). We have investigated the association of six single nucleotide polymorphisms within the NR4A family of genes with TD in a sample of 171 patients with schizophrenia of Caucasian descent. The NR4A1 single nucleotide polymorphism (SNP) marker rs2603751 showed a nominal association with the...
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