Article
Fine mapping of Leishmania major susceptibility Locus lmr2 and evidence of a role for Fli1 in disease and wound healing.
Infection and immunity - 1 Jun 2010
Sakthianandeswaren Anuratha, Curtis Joan M, Elso Colleen, Kumar Beena, Baldwin Tracey M, Lopaticki Sash, Kedzierski Lukasz, Smyth Gordon K, Foote Simon J, Handman Emanuela
Abstract excerpt
Genetic linkage studies of the host response to Leishmania major, the causative agent of cutaneous leishmaniasis, have identified significant genetic complexity in humans and mice. In the mouse model, multiple loci have been implicated in susceptibility to infection, but to date, the genes underlying these loci have not been identified. We now describe the contribution of a novel candidate gene, Fli1, to both L....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.