Article
The wound repair response controls outcome to cutaneous leishmaniasis.
Proceedings of the National Academy of Sciences of the United States of America - 25 Oct 2005
Sakthianandeswaren Anuratha, Elso Colleen M, Simpson Ken, Curtis Joan M, Kumar Beena, Speed Terence P, Handman Emanuela, Foote Simon J
Abstract excerpt
Chronic microbial infections are associated with fibrotic and inflammatory reactions known as granulomas showing similarities to wound-healing and tissue repair processes. We have previously mapped three leishmaniasis susceptibility loci, designated lmr1, -2, and -3, which exert their effect independently of T cell immune responses. Here, we show that the wound repair response is critically important for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.