Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FLI1 polymorphism affects susceptibility to cutaneous leishmaniasis in Brazil.

Genes and immunity - 1 Oct 2011

Castellucci L, Jamieson S E, Miller E N, de Almeida L F, Oliveira J, Magalhães A, Guimarães L H, Lessa M, Lago E, de Jesus A R, Carvalho E M, Blackwell J M

Abstract excerpt

Mapping murine genes controlling cutaneous leishmaniasis (CL) identified Fli1 as a candidate influencing resistance to L. major and enhanced wound healing. We examine FLI1 as a gene controlling CL and mucosal leishmaniasis (ML) caused by L. braziliensis in humans. Intron 1 single nucleotide polymorphisms tagging promoter and enhancer elements were analysed in 168 nuclear families (250 CL; 87 ML cases) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Introns

Share to Leishmaniasis, Cutaneous

Share to Proto-Oncogene Protein c-fli-1

Share to Racial Groups

Source

Open in PubMed Open full text

Identifiers

PMID: 21633373
DOI: 10.1038/gene.2011.37
PMCID: PMC3297968

Genes

FLI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FLI1 polymorphism affects susceptibility to cutaneous leishmaniasis in Brazil.PMID 21633373Read ↗

Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil: role of COL1A1.Semantic proximity Read ↗

Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil.Semantic proximity Read ↗

Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil.Semantic proximity Read ↗

FLI1 gene influences lesion size and skin test may predict therapeutic response in cutaneous leishmaniasis.Semantic proximity Read ↗

A genome-wide association study highlights a regulatory role for <i>IFNG-AS1</i> contributing to cutaneous leishmaniasis in BrazilSemantic proximity Read ↗

Fine mapping of Leishmania major susceptibility Locus lmr2 and evidence of a role for Fli1 in disease and wound healing.Semantic proximity Read ↗

CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study.Semantic proximity Read ↗

Genomic Profiling of Human Leishmania braziliensis Lesions Identifies Transcriptional Modules Associated with Cutaneous ImmunopathologySemantic proximity Read ↗

The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil.Semantic proximity Read ↗

<i>IL6</i>−174 G/C Promoter Polymorphism Influences Susceptibility to Mucosal but Not Localized Cutaneous Leishmaniasis in BrazilSemantic proximity Read ↗

A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil.Semantic proximity Read ↗

A Single Haplotype of IFNG Correlating With Low Circulating Levels of Interferon-γ Is Associated With Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.