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Article

Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2012

Castellucci Léa, Jamieson Sarra E, Almeida Lucas, Oliveira Joyce, Guimarães Luiz Henrique, Lessa Marcus, Fakiola Michaela, Jesus Amélia Ribeiro de, Nancy Miller E, Carvalho Edgar M, Blackwell Jenefer M

Abstract excerpt

Leishmania braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. In the mouse, Fli1 was identified as a gene influencing enhanced wound healing and resistance to CL caused by Leishmania major. Polymorphism at FLI1 is associated with CL caused by L. braziliensis in humans, with an inverse association observed for ML disease. Here we extend the analysis to look at other wound healing genes, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22554650
DOI: 10.1016/j.meegid.2012.03.017
PMCID: PMC3372530

Genes

FLI1
SMAD2
SMAD7
FLII
SMAD3
TGFBR2
TGFB1
TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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