Article
Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes.
Human genomics - 1 Feb 2010
Mosconi Lisa, Berti Valentina, Swerdlow Russell H, Pupi Alberto, Duara Ranjan, de Leon Mony
Abstract excerpt
After advanced age, having a parent affected with Alzheimer's disease (AD) is the most significant risk factor for developing AD among cognitively normal (NL) individuals. Although rare genetic mutations have been identified among the early-onset forms of familial AD (EOFAD), the genetics of the more common forms of late-onset AD (LOAD) remain elusive. While some LOAD cases appear to be sporadic in nature,...
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