Article
Polarized targeting of DNER into dendritic plasma membrane in hippocampal neurons depends on endocytosis.
Journal of neurochemistry - 1 Jun 2010
Kurisu Junko, Fukuda Tetsuko, Yokoyama Seisuke, Hirano Tomoo, Kengaku Mineko
Abstract excerpt
The targeting of membrane proteins into axons and dendrites is of critical importance for directional signal transmission within specific neural circuits. Many dendritic proteins have been shown to reach the somatodendritic membrane based on selective sorting and transport of carrier vesicles. Using rat hippocampal neurons in culture, we investigated the trafficking pathways of Delta/Notch-like EGF-related...
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